{
  "schema_version": 1,
  "constructs": [
    {
      "id": "example-injected-slp",
      "sequence": "RISVTPGEKIILNFTTLDLYRSR",
      "delivery": "synthetic_long_peptide",
      "intended_epitopes": [
        {"label": "mutant target", "start": 9, "end": 17}
      ],
      "mhc_windows": [
        {"mhc_class": "I", "allele": "HLA-A*02:01", "start": 9, "end": 17, "percentile_rank": 0.4, "predictor": "example-I"},
        {"mhc_class": "II", "allele": "HLA-DRB1*03:01", "start": 4, "end": 18, "percentile_rank": 1.8, "predictor": "example-II"}
      ],
      "cleavage_tracks": [
        {
          "name": "example proteasome",
          "context": "cytosolic_proteasome",
          "evidence_type": "quantitative_model",
          "scores": [0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 0.8, 0.7, 0.6, 0.5, 0.4, 0.3, 0.2, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6],
          "threshold": 0.5,
          "units": "dimensionless native output",
          "provenance": "example only"
        },
        {
          "name": "example endolysosomal",
          "context": "endolysosomal",
          "evidence_type": "quantitative_model",
          "scores": [0.6, 0.3, 0.2, 0.1, 0.2, 0.4, 0.7, 0.9, 0.4, 0.2, 0.1, 0.3, 0.5, 0.8, 0.7, 0.4, 0.2, 0.1, 0.2, 0.3, 0.4, 0.5],
          "threshold": 0.5,
          "units": "dimensionless native output",
          "provenance": "example only"
        },
        {
          "name": "example MME",
          "context": "extracellular_interstitial",
          "evidence_type": "motif_rule",
          "scores": [0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0],
          "threshold": 1,
          "units": "binary motif decision",
          "provenance": "example only"
        }
      ]
    },
    {
      "id": "example-cytosolic-rna",
      "sequence": "MRISVTPGEKIILNFTTLDLYRSR",
      "delivery": "rna_encoded",
      "routing": "cytosolic",
      "intended_epitopes": [
        {"label": "encoded target", "start": 10, "end": 18}
      ],
      "mhc_windows": [
        {"mhc_class": "I", "allele": "HLA-A*02:01", "start": 10, "end": 18, "percentile_rank": 0.4, "predictor": "example-I"}
      ],
      "cleavage_tracks": [
        {
          "name": "example proteasome",
          "context": "cytosolic_proteasome",
          "evidence_type": "quantitative_model",
          "scores": [null, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 0.8, 0.7, 0.6, 0.5, 0.4, 0.3, 0.2, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6],
          "threshold": 0.5,
          "units": "dimensionless native output",
          "provenance": "example only"
        }
      ]
    }
  ]
}